Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FOXO1 All Species: 19.09
Human Site: S448 Identified Species: 42
UniProt: Q12778 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q12778 NP_002006.2 655 69662 S448 T L Q D N K S S Y G G M S Q Y
Chimpanzee Pan troglodytes XP_522749 829 87557 S622 T L Q D N K S S Y G G M S Q Y
Rhesus Macaque Macaca mulatta XP_001088437 860 91177 S653 T L Q D N K S S Y G G M S Q Y
Dog Lupus familis XP_534487 524 56894 G319 Q D N K S S F G G M N Q Y N C
Cat Felis silvestris
Mouse Mus musculus Q9R1E0 652 69484 S445 T L Q D S K S S Y G G L N Q Y
Rat Rattus norvegicus XP_342245 649 69326 S442 T L Q D S K S S Y G G L N Q Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512968 514 54918 G309 P M Q T L P D G K S G Y G G L
Chicken Gallus gallus Q90964 451 48838 L246 S T T S R A K L A F K R G A R
Frog Xenopus laevis Q6EUW2 631 68449 P422 I S P I S Q M P M Q T V P E N
Zebra Danio Brachydanio rerio NP_001070725 652 69329 G441 K P S F G P G G G T M G Q F N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q95V55 613 67394 S408 Y P N S E P S S D S L N T Y S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 79 75.4 74.8 N.A. 92.6 92.2 N.A. 63.3 21.9 66.4 59.3 N.A. 29.7 N.A. N.A. N.A.
Protein Similarity: 100 79 75.6 77.2 N.A. 95.5 95.2 N.A. 69.9 35.4 76.7 72 N.A. 41.9 N.A. N.A. N.A.
P-Site Identity: 100 100 100 0 N.A. 80 80 N.A. 13.3 0 0 0 N.A. 13.3 N.A. N.A. N.A.
P-Site Similarity: 100 100 100 6.6 N.A. 100 100 N.A. 20 6.6 26.6 0 N.A. 20 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 10 0 0 10 0 0 0 0 10 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % C
% Asp: 0 10 0 46 0 0 10 0 10 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 10 0 0 0 0 0 0 0 0 10 0 % E
% Phe: 0 0 0 10 0 0 10 0 0 10 0 0 0 10 0 % F
% Gly: 0 0 0 0 10 0 10 28 19 46 55 10 19 10 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 10 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 10 0 0 10 0 46 10 0 10 0 10 0 0 0 0 % K
% Leu: 0 46 0 0 10 0 0 10 0 0 10 19 0 0 10 % L
% Met: 0 10 0 0 0 0 10 0 10 10 10 28 0 0 0 % M
% Asn: 0 0 19 0 28 0 0 0 0 0 10 10 19 10 19 % N
% Pro: 10 19 10 0 0 28 0 10 0 0 0 0 10 0 0 % P
% Gln: 10 0 55 0 0 10 0 0 0 10 0 10 10 46 0 % Q
% Arg: 0 0 0 0 10 0 0 0 0 0 0 10 0 0 10 % R
% Ser: 10 10 10 19 37 10 55 55 0 19 0 0 28 0 10 % S
% Thr: 46 10 10 10 0 0 0 0 0 10 10 0 10 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 10 0 0 0 0 0 0 0 46 0 0 10 10 10 46 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _